HitPredict

Interactor 1: DPH2 (P32461)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)
Gene: DPH2

Interactor 2: HSP7E (P39987)
Heat shock protein SSC3, mitochondrial (Extracellular mutant protein 10)
Gene: ECM10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	16554755, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 534 Sc			1 644
+	Sc
		478008 DPH2_YEAST (1-534): 0: 641: 100.00		HSP77_YEAST (14-631): 0: 969: 83.33
+	Sc
		478256 DPH1_YEAST (12-420): 5.48e-131: 389: 18.59		HSP77_YEAST (14-631): 0: 969: 83.33
+	Hs
		504709 DPH1_HUMAN (27-466): 1.05e-158: 460: 18.82		HSP7C_HUMAN (25-631): 0: 885: 47.42
+	Hs
		504657 DPH2_HUMAN (6-524): 2.93e-152: 446: 23.03		HSP7C_HUMAN (25-631): 0: 885: 47.42
+	Sc
		766046 DPH1_YEAST (12-420): 5.48e-131: 389: 18.59		HSP7E_YEAST (1-644): 0: 895: 100.00
+	Hs
		502517 DPH1_HUMAN (27-466): 1.05e-158: 460: 18.82		BIP_HUMAN (29-637): 1.81e-179: 526: 48.71
+	Sc
		774557 DPH1_YEAST (12-420): 5.48e-131: 389: 18.59		HSP7Q_YEAST (8-634): 0: 577: 52.31