HitPredict

Interactor 1: EF1B (P32471)
Elongation factor 1-beta (EF-1-beta) (Eukaryotic elongation factor 1Balpha) (eEF1Balpha) (Translation elongation factor 1B alpha)
Gene: EFB1

Interactor 2: EF1G2 (P36008)
Elongation factor 1-gamma 2 (EF-1-gamma 2) (Eukaryotic elongation factor 1Bgamma 2) (eEF1Bgamma 2) (Translation elongation factor 1B gamma 2)
Gene: TEF4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.701

Property	Details
Experiments	11805826, 17179749, 16429126, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003746 - translation elongation factor activity GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005840 - ribosome GO:0005853 - eukaryotic translation elongation factor 1 complex GO:0006414 - translational elongation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 206 Sc			1 412
+	Mm
		250576 EF1B_MOUSE (1-206): 1.17e-89: 264: 45.58		EF1G_MOUSE (1-412): 6.25e-153: 441: 29.27
+	Hs
		623067 EF1B_HUMAN (1-206): 2.08e-90: 266: 46.46		EF1G_HUMAN (1-412): 4.45e-152: 439: 29.49
+	Hs
		643935 EF1D_HUMAN (6-206): 1.61e-83: 250: 43.07		EF1G_HUMAN (1-412): 4.45e-152: 439: 29.49
+	Os
		1114552 EF1D2_ORYSJ (1-206): 2.08e-75: 228: 35.50		EF1G3_ORYSJ (1-412): 7.16e-159: 455: 29.11
+	Os
		1114550 EF1D1_ORYSJ (1-206): 2.17e-74: 225: 33.76		EF1G3_ORYSJ (1-412): 7.16e-159: 455: 29.11
+	At
		1325183 EF1D2_ARATH (2-206): 8.3e-81: 241: 32.64		EF1G2_ARATH (1-412): 3.5e-152: 438: 28.61
+	Os
		1114553 EF1D2_ORYSJ (1-206): 2.08e-75: 228: 35.50		EF1G2_ORYSJ (1-412): 2.87e-156: 449: 28.83
+	Os
		1114555 EF1D2_ORYSJ (1-206): 2.08e-75: 228: 35.50		EF1G1_ORYSJ (1-412): 6.36e-153: 440: 26.87
+	Os
		1114551 EF1D1_ORYSJ (1-206): 2.17e-74: 225: 33.76		EF1G1_ORYSJ (1-412): 6.36e-153: 440: 26.87
+	Sc
		668181 EF1B_YEAST (1-206): 3.97e-71: 216: 100.00		EF1G1_YEAST (1-412): 6.62e-146: 422: 62.17
+	Dm
		332297 EF1B_DROME (1-206): 1.85e-78: 235: 51.34		EF1G_DROME (1-412): 8.03e-127: 374: 27.90
+	Dm
		1342165 EF1D_DROME (69-206): 8.36e-50: 164: 54.35		EF1G_DROME (1-412): 8.03e-127: 374: 27.90
+	Sp
		251159 EF1B_SCHPO (1-206): 4.07e-78: 234: 50.00		YC12_SCHPO (1-219): 5.84e-58: 190: 25.78
+	Hs
		623066 EF1B_HUMAN (1-206): 2.08e-90: 266: 46.46		SYVC_HUMAN (5-239): 3.13e-29: 122: 23.14
+	Hs
		643813 EF1D_HUMAN (6-206): 1.61e-83: 250: 43.07		SYVC_HUMAN (5-239): 3.13e-29: 122: 23.14
+	Dm
		55769 EF1D_DROME (69-206): 8.36e-50: 164: 54.35		A1ZB71_DROME (1-204): 1.29e-53: 179: 17.54