HitPredict

Interactor 1: HIR1 (P32479)
Protein HIR1 (Histone transcription regulator 1)
Gene: HIR1

Interactor 2: HIR2 (P32480)
Protein HIR2 (Histone transcription regulator 2)
Gene: HIR2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 9504914, 9001207, 16264190, 21782987, 37968396, 21179020
Identification Methods coimmunoprecipitation, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hira~Hira
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000417 - HIR complex
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0006325 - chromatin organization
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 840
Sc

1 875
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024