HitPredict

Interactor 1: A9CQL4 (A9CQL4)
Centriole protein
Gene: CrSAS-6

Interactor 2: A9CQL4 (A9CQL4)
Centriole protein
Gene: CrSAS-6

Species: Chlamydomonas reinhardtii

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	26999736, 21277013
Identification Methods	atomic force microscopy, isothermal titration calorimetry, fluorescence polarization spectroscopy, cross-linking study, cosedimentation in solution, transmission electron microscopy, x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAS-6_N~SAS-6_N
Common GO terms	GO:0005737 - cytoplasm GO:0005814 - centriole GO:0007049 - cell cycle
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 728 Cr			1 728
+	Dm
		1361112 SAS6_DROME (54-501): 9.32e-62: 216: 20.26		SAS6_DROME (54-501): 9.32e-62: 216: 20.26
+	Hs
		255230 LIPA3_HUMAN (41-609): 5.72e-30: 129: 13.32		LIPA3_HUMAN (41-609): 5.72e-30: 129: 13.32
+	Rn
		1186812 MRCKB_RAT (67-676): 5.4e-26: 117: 9.49		MRCKB_RAT (67-676): 5.4e-26: 117: 9.49
+	Hs
		255242 LIPA3_HUMAN (41-609): 5.72e-30: 129: 13.32		LIPA1_HUMAN (35-461): 1.02e-14: 80.4: 14.42
+	Hs
		1268060 MY18A_HUMAN (168-526): 1.64e-20: 99.3: 12.91		MY18A_HUMAN (168-526): 1.64e-20: 99.3: 12.91
+	Hs
		1268099 MY18A_HUMAN (168-526): 1.64e-20: 99.3: 12.91		MYO5C_HUMAN (1-371): 2.22e-20: 99.1: 11.55
+	Rn
		222476 MRCKB_RAT (67-676): 5.4e-26: 117: 9.49		MRCKA_RAT (2-324): 2.76e-14: 79.3: 11.94
+	Hs
		1268126 MY18A_HUMAN (168-526): 1.64e-20: 99.3: 12.91		MRCKB_HUMAN (268-574): 2.68e-19: 95.5: 13.03
+	Hs
		254476 ROCK2_HUMAN (105-521): 3.35e-21: 101: 11.42		ROCK1_HUMAN (136-557): 2.52e-17: 89: 10.73
+	Bt
		1100183 ROCK2_BOVIN (145-505): 4.6e-19: 94.7: 12.31		ROCK2_BOVIN (145-505): 4.6e-19: 94.7: 12.31
+	Hs
		528432 MYH13_HUMAN (1-530): 2.15e-20: 99: 11.87		MYH8_HUMAN (192-592): 3.87e-17: 88.6: 12.38
+	Hs
		551596 DESP_HUMAN (3-424): 7.12e-18: 90.8: 10.61		DESP_HUMAN (3-424): 7.12e-18: 90.8: 10.61
+	Hs
		724943 MY18A_HUMAN (168-526): 1.64e-20: 99.3: 12.91		MYH9_HUMAN (1-368): 6.96e-12: 71.2: 9.90
+	Hs
		725035 MYO5C_HUMAN (1-371): 2.22e-20: 99.1: 11.55		MYH9_HUMAN (1-368): 6.96e-12: 71.2: 9.90
+	Hs
		149126 MY18A_HUMAN (168-526): 1.64e-20: 99.3: 12.91		CTRO_HUMAN (255-530): 4.29e-11: 69: 8.70
+	Hs
		1137917 MRCKB_HUMAN (268-574): 2.68e-19: 95.5: 13.03		MRCKA_HUMAN (2-324): 2.87e-11: 69.3: 11.34
+	Hs
		148359 DESP_HUMAN (3-424): 7.12e-18: 90.8: 10.61		CTRO_HUMAN (255-530): 4.29e-11: 69: 8.70
+	Rn
		92843 ROCK2_RAT (145-501): 3.72e-19: 94.7: 12.12		CTRO_RAT (255-549): 1.31e-09: 64: 13.87