Interactor 1: A9UEZ6 (A9UEZ6)
non-specific protein-tyrosine kinase (EC 2.7.10.2)
Gene: BCR/ABL

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned1853
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains COR~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase, LRR_8~SH2
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005096 - GTPase activator activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1633
Hs

1 2527
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024