Interactor 1: A9UF07 (A9UF07)
non-specific protein-tyrosine kinase (EC 2.7.10.2)
Gene: BCR/ABL

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.39 1.00 0.625

The method score is based on:

Property Details
Experiments 19380743
Identification Methods anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0007165 - signal transduction
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1790
Hs

1 217
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024