HitPredict

Interactor 1: PAN1 (P32521)
Actin cytoskeleton-regulatory complex protein PAN1 (Mitochondrial distribution of proteins protein 3)
Gene: PAN1

Interactor 2: ARPC1 (P38328)
Actin-related protein 2/3 complex subunit 1 (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARC40

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11433303, 37968396
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030479 - actin cortical patch GO:2000601 - positive regulation of Arp2/3 complex-mediated actin nucleation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Sc			1 384
+	Hs
		1281436 EHD2_HUMAN (229-695): 4.13e-62: 224: 14.02		FBXW7_HUMAN (1-321): 3.45e-66: 224: 11.89
+	Hs
		903517 EHD1_HUMAN (232-691): 9.44e-62: 223: 15.67		WDR5_HUMAN (182-383): 7.51e-36: 135: 12.75
+	Hs
		283022 EHD1_HUMAN (232-691): 9.44e-62: 223: 15.67		CIAO1_HUMAN (7-142): 6.72e-21: 94.4: 14.56
+	Hs
		1057782 NCOA6_HUMAN (66-1164): 1.04e-11: 72.2: 8.36		FBXW7_HUMAN (1-321): 3.45e-66: 224: 11.89
+	Hs
		60139 XIRP2_HUMAN (529-1474): 3.09e-42: 172: 9.66		CIAO1_HUMAN (7-142): 6.72e-21: 94.4: 14.56
+	Hs
		903229 NCOA6_HUMAN (66-1164): 1.04e-11: 72.2: 8.36		WDR5_HUMAN (182-383): 7.51e-36: 135: 12.75