HitPredict

Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: RSMB (P40018)
Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB)
Gene: SMB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	11884590, 11804584, 37968396, 21558325
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 503 Sc			1 196
+	Sp
		144114 PRP19_SCHPO (1-480): 1.74e-82: 265: 20.04		RSMB_SCHPO (9-108): 7.53e-38: 129: 39.00
+	Hs
		538887 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58
+	Hs
		539186 PRP19_HUMAN (284-502): 2.22e-40: 153: 9.78		RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58
+	Hs
		196951 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		RSMB_HUMAN (4-104): 8.53e-43: 145: 41.58
+	Hs
		196997 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		RSMN_HUMAN (4-104): 4.51e-43: 145: 41.58