HitPredict

Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: TCPQ (P47079)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta)
Gene: CCT8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 503 Sc			1 568
+	Hs
		826946 WDR37_HUMAN (57-450): 1.89e-72: 239: 13.94		TCPG_HUMAN (10-567): 0: 562: 24.82
+	Hs
		1306747 WDR37_HUMAN (57-450): 1.89e-72: 239: 13.94		TCPH_HUMAN (10-558): 0: 552: 25.09
+	Hs
		573535 WDR37_HUMAN (57-450): 1.89e-72: 239: 13.94		TCPA_HUMAN (20-555): 0: 543: 26.52
+	Hs
		792942 LIS1_HUMAN (34-403): 4.77e-55: 191: 10.18		TCPG_HUMAN (10-567): 0: 562: 24.82
+	Hs
		842812 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		TCPQ_HUMAN (1-568): 0: 567: 45.34
+	Hs
		826601 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		TCPG_HUMAN (10-567): 0: 562: 24.82
+	Hs
		826748 WDR5B_HUMAN (262-502): 3.68e-50: 176: 12.40		TCPG_HUMAN (10-567): 0: 562: 24.82
+	Hs
		903467 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		TCPH_HUMAN (10-558): 0: 552: 25.09
+	Hs
		1202777 WDR5B_HUMAN (262-502): 3.68e-50: 176: 12.40		TCPH_HUMAN (10-558): 0: 552: 25.09
+	Hs
		821152 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		TCPE_HUMAN (9-544): 0: 544: 25.33
+	Hs
		573201 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		TCPA_HUMAN (20-555): 0: 543: 26.52
+	Hs
		573346 WDR5B_HUMAN (262-502): 3.68e-50: 176: 12.40		TCPA_HUMAN (20-555): 0: 543: 26.52
+	Hs
		196978 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		TCPQ_HUMAN (1-568): 0: 567: 45.34
+	Hs
		196973 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		TCPG_HUMAN (10-567): 0: 562: 24.82
+	Hs
		826605 GBB2_HUMAN (278-502): 5.62e-39: 146: 10.13		TCPG_HUMAN (10-567): 0: 562: 24.82
+	Hs
		197078 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		TCPH_HUMAN (10-558): 0: 552: 25.09
+	Hs
		196971 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		TCPE_HUMAN (9-544): 0: 544: 25.33
+	Hs
		196954 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		TCPA_HUMAN (20-555): 0: 543: 26.52
+	Hs
		821157 GBB2_HUMAN (278-502): 5.62e-39: 146: 10.13		TCPE_HUMAN (9-544): 0: 544: 25.33
+	Hs
		573205 GBB2_HUMAN (278-502): 5.62e-39: 146: 10.13		TCPA_HUMAN (20-555): 0: 543: 26.52