HitPredict

Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: RUXF (P54999)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SMX3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	11805826, 11884590, 11804584, 37968396, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 503 Sc			1 86
+	Sc
		692360 PRP19_YEAST (1-503): 7.56e-93: 293: 100.00		LSM6_YEAST (4-83): 8.53e-21: 80.1: 26.19
+	Sp
		144083 PRP19_SCHPO (1-480): 1.74e-82: 265: 20.04		RUXF_SCHPO (9-83): 6.68e-32: 107: 60.00
+	Hs
		903090 WDR5_HUMAN (262-502): 3.82e-53: 184: 13.64		RUXF_HUMAN (12-84): 3.52e-34: 113: 57.53
+	Hs
		911996 PRP19_HUMAN (284-502): 2.22e-40: 153: 9.78		RUXF_HUMAN (12-84): 3.52e-34: 113: 57.53
+	Hs
		196988 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		RUXF_HUMAN (12-84): 3.52e-34: 113: 57.53
+	Hs
		196991 PRP4_HUMAN (293-502): 1.86e-39: 151: 11.87		LSM6_HUMAN (9-83): 1.57e-33: 112: 40.00