Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19
Interactor 2: CEF1 (Q03654)
Pre-mRNA-splicing factor CEF1 (PRP nineteen-associated complex protein 85) (PRP19-associated complex protein 85)
Gene: CEF1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.989 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10092627, 11842115, 11805826, 11805837, 11884590, 11804584, 11018040, 16357217, 17515604, 19617314, 37968396, 19704000, 20956557, 14759368, 15601865, 16429126, 25294830, 29146870, 30879786 |
| Identification Methods | genetic interference, filter binding, coimmunoprecipitation, affinity chromatography technology, two hybrid, biochemical, tandem affinity purification, anti tag coimmunoprecipitation, far western blotting, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Myb_Cef~Prp19 |
| Common GO terms | GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0005737 - cytoplasm GO:0071006 - U2-type catalytic step 1 spliceosome |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
