HitPredict

Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: PRP46 (Q12417)
Pre-mRNA-splicing factor PRP46 (Complexed with CEF1 protein 1) (PRP nineteen-associated complex protein 50) (PRP19-associated complex protein 50) (Pre-mRNA-processing protein 46)
Gene: PRP46

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.744

The method score is based on:

Property Details
Experiments 11805826, 11884590, 11804584, 16554755, 16429126, 37968396, 11842115
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005737 - cytoplasm
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 503
Sc

1 451
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024