HitPredict

Interactor 1: SPT16 (P32558)
FACT complex subunit SPT16 (Cell division control protein 68) (Facilitates chromatin transcription complex subunit SPT16) (Suppressor of Ty protein 16)
Gene: SPT16

Interactor 2: RSC4 (Q02206)
Chromatin structure-remodeling complex subunit RSC4 (RSC complex subunit RSC4) (Remodel the structure of chromatin complex subunit 4)
Gene: RSC4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	14729968, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006368 - transcription elongation by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1035 Sc			1 625
+	Hs
		1262849 SP16H_HUMAN (4-1028): 0: 1082: 32.76		PHIP_HUMAN (16-470): 3.23e-64: 232: 15.67
+	Sc
		692742 SPT16_YEAST (1-1035): 0: 1136: 100.00		BDF1_YEAST (117-384): 5.12e-22: 102: 15.22
+	Sc
		692895 SPT16_YEAST (1-1035): 0: 1136: 100.00		GCN5_YEAST (5-160): 4.11e-20: 95.3: 16.77
+	Sc
		692942 SPT16_YEAST (1-1035): 0: 1136: 100.00		BDF2_YEAST (6-210): 9.77e-18: 89.2: 14.29
+	Sc
		692934 SPT16_YEAST (1-1035): 0: 1136: 100.00		RSC2_YEAST (55-196): 1.71e-13: 76.1: 19.01
+	Hs
		999254 SP16H_HUMAN (4-1028): 0: 1082: 32.76		EP300_HUMAN (4-210): 2.62e-21: 101: 14.35
+	Hs
		245135 SP16H_HUMAN (4-1028): 0: 1082: 32.76		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05