HitPredict

Interactor 1: RPD3 (P32561)
Histone deacetylase RPD3 (EC 3.5.1.98) (Transcriptional regulatory protein RPD3)
Gene: RPD3

Interactor 2: TCPB (P39076)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)
Gene: CCT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	23878396
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Sc			1 527
+	Hs
		1038670 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPH_HUMAN (2-517): 0: 570: 34.36
+	Hs
		826651 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPG_HUMAN (2-525): 0: 552: 27.15
+	Hs
		943219 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Sc
		693035 RPD3_YEAST (1-433): 0: 599: 100.00		TCPH_YEAST (3-527): 0: 537: 32.26
+	Hs
		826803 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPG_HUMAN (2-525): 0: 552: 27.15
+	Sc
		693017 RPD3_YEAST (1-433): 0: 599: 100.00		TCPG_YEAST (2-522): 0: 527: 27.05
+	Hs
		573251 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		821200 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Hs
		573401 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		821342 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Hs
		177367 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPH_HUMAN (2-517): 0: 570: 34.36
+	Hs
		177233 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPG_HUMAN (2-525): 0: 552: 27.15
+	Hs
		177257 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Sp
		140638 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPH_SCHPO (1-524): 0: 559: 32.83
+	Hs
		177188 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		177231 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Sp
		140519 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPG_SCHPO (2-523): 0: 537: 26.37
+	Sp
		140663 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPB_SCHPO (2-524): 0: 523: 68.45
+	Sc
		693029 RPD3_YEAST (1-433): 0: 599: 100.00		TCPE_YEAST (5-515): 1.24e-77: 256: 35.09
+	Sp
		140614 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPD_SCHPO (13-518): 3.25e-78: 256: 33.33