HitPredict

Interactor 1: RPD3 (P32561)
Histone deacetylase RPD3 (EC 3.5.1.98) (Transcriptional regulatory protein RPD3)
Gene: RPD3

Interactor 2: TCPG (P39077)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma)
Gene: CCT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	23878396
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Sc			1 534
+	Hs
		826651 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPG_HUMAN (2-533): 0: 585: 59.48
+	Hs
		843190 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPD_HUMAN (11-528): 0: 583: 31.87
+	Hs
		826803 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPG_HUMAN (2-533): 0: 585: 59.48
+	Hs
		1038670 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPH_HUMAN (1-532): 0: 561: 30.61
+	Hs
		821200 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPE_HUMAN (2-534): 0: 537: 32.41
+	Sc
		693035 RPD3_YEAST (1-433): 0: 599: 100.00		TCPH_YEAST (2-533): 0: 530: 28.94
+	Hs
		573251 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPA_HUMAN (1-534): 0: 529: 29.75
+	Hs
		821342 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPE_HUMAN (2-534): 0: 537: 32.41
+	Hs
		177233 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPG_HUMAN (2-533): 0: 585: 59.48
+	Hs
		177239 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPD_HUMAN (11-528): 0: 583: 31.87
+	Hs
		573401 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPA_HUMAN (1-534): 0: 529: 29.75
+	Sp
		140519 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPG_SCHPO (1-532): 0: 587: 68.61
+	Hs
		177367 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPH_HUMAN (1-532): 0: 561: 30.61
+	Sc
		760777 HOS2_YEAST (3-430): 3.66e-168: 481: 45.04		TCPG_YEAST (1-534): 0: 601: 100.00
+	Hs
		177231 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPE_HUMAN (2-534): 0: 537: 32.41
+	Sp
		140638 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPH_SCHPO (2-534): 0: 556: 30.19
+	Hs
		177188 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPA_HUMAN (1-534): 0: 529: 29.75
+	Sp
		140725 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPE_SCHPO (4-534): 0: 528: 32.16
+	Sc
		792389 HOS2_YEAST (3-430): 3.66e-168: 481: 45.04		TCPH_YEAST (2-533): 0: 530: 28.94
+	Mm
		516943 HDAC4_MOUSE (1-418): 6.97e-134: 412: 22.77		TCPA_MOUSE (1-534): 0: 587: 29.02