HitPredict

Interactor 1: RPD3 (P32561)
Histone deacetylase RPD3 (EC 3.5.1.98) (Transcriptional regulatory protein RPD3)
Gene: RPD3

Interactor 2: TCPD (P39078)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta)
Gene: CCT4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	23878396
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Sc			1 528
+	Hs
		573251 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPA_HUMAN (8-525): 0: 587: 30.97
+	Hs
		573401 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPA_HUMAN (8-525): 0: 587: 30.97
+	Hs
		1038670 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPH_HUMAN (1-527): 0: 568: 29.64
+	Hs
		843190 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPD_HUMAN (11-528): 0: 564: 59.42
+	Hs
		826651 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPG_HUMAN (2-525): 0: 562: 29.68
+	Sc
		693017 RPD3_YEAST (1-433): 0: 599: 100.00		TCPG_YEAST (1-525): 0: 549: 27.05
+	Hs
		821200 HDAC1_HUMAN (15-428): 0: 598: 60.87		TCPE_HUMAN (5-524): 0: 547: 35.76
+	Hs
		826803 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPG_HUMAN (2-525): 0: 562: 29.68
+	Sc
		693035 RPD3_YEAST (1-433): 0: 599: 100.00		TCPH_YEAST (2-528): 0: 538: 28.20
+	Hs
		821342 HDAC2_HUMAN (18-432): 0: 583: 61.69		TCPE_HUMAN (5-524): 0: 547: 35.76
+	Hs
		177188 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPA_HUMAN (8-525): 0: 587: 30.97
+	Hs
		177367 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPH_HUMAN (1-527): 0: 568: 29.64
+	Hs
		177239 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPD_HUMAN (11-528): 0: 564: 59.42
+	Hs
		177233 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPG_HUMAN (2-525): 0: 562: 29.68
+	Hs
		177231 HDAC3_HUMAN (19-433): 0: 534: 57.31		TCPE_HUMAN (5-524): 0: 547: 35.76
+	Sp
		140519 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPG_SCHPO (1-525): 0: 563: 31.38
+	Sp
		140638 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPH_SCHPO (2-527): 0: 557: 29.32
+	Sp
		140614 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPD_SCHPO (1-528): 0: 556: 66.92
+	Sp
		140725 PHD1_SCHPO (4-414): 3.57e-179: 508: 50.60		TCPE_SCHPO (5-527): 0: 541: 34.79
+	Sc
		693029 RPD3_YEAST (1-433): 0: 599: 100.00		TCPE_YEAST (12-527): 1.47e-98: 310: 35.55