HitPredict

Interactor 1: CDC5 (P32562)
Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC 2.7.11.21)
Gene: CDC5

Interactor 2: SMC1 (P32908)
Structural maintenance of chromosomes protein 1 (DA-box protein SMC1)
Gene: SMC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	11805837, 19013276, 20489023
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 1225
+	Sc
		693130 CDC5_YEAST (1-705): 0: 628: 100.00		SMC3_YEAST (3-1221): 2.09e-67: 251: 15.88
+	Hs
		861755 PLK1_HUMAN (88-704): 4.2e-159: 474: 29.81		SMC1A_HUMAN (1-1225): 2.94e-92: 325: 26.86
+	Hs
		610795 KAPCB_HUMAN (80-370): 3.38e-41: 155: 32.14		MYH2_HUMAN (484-1130): 7.06e-20: 98.6: 8.59
+	Hs
		522538 KAPCB_HUMAN (80-370): 3.38e-41: 155: 32.14		MYH1_HUMAN (653-1140): 4.3e-16: 86.3: 13.39
+	Hs
		522582 AURKC_HUMAN (70-343): 4.15e-41: 154: 32.26		MYH1_HUMAN (653-1140): 4.3e-16: 86.3: 13.39
+	Hs
		522653 AURKC_HUMAN (70-343): 4.15e-41: 154: 32.26		MYH7_HUMAN (60-672): 2.23e-15: 84: 11.01
+	Hs
		528359 KAPCB_HUMAN (80-370): 3.38e-41: 155: 32.14		MYH6_HUMAN (53-660): 2.33e-13: 77.4: 11.11
+	Hs
		528433 AURKC_HUMAN (70-343): 4.15e-41: 154: 32.26		MYH8_HUMAN (788-1125): 8.79e-12: 72: 10.26