HitPredict

Interactor 1: VPP1 (P32563)
V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)
Gene: VPH1

Interactor 2: VPP1 (P32563)
V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)
Gene: VPH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.820

The method score is based on:

Property	Details
Experiments	18307317, 19081055, 22367203
Identification Methods	unspecified method, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	V_ATPase_I~V_ATPase_I
Common GO terms	GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain GO:0000324 - fungal-type vacuole GO:0000329 - fungal-type vacuole membrane GO:0005886 - plasma membrane GO:0006797 - polyphosphate metabolic process and 9 others more... GO:0007035 - vacuolar acidification GO:0016471 - vacuolar proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0051117 - ATPase binding GO:0065003 - protein-containing complex assembly GO:0071469 - cellular response to alkaline pH GO:0071474 - cellular hyperosmotic response GO:0080025 - phosphatidylinositol-3,5-bisphosphate binding GO:1902600 - proton transmembrane transport
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	840
Sc

1	840

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Last updated: 15 Jul 2024