Interactor 1: MED17 (P32569)
Mediator of RNA polymerase II transcription subunit 17 (Mediator complex subunit 17) (Suppressor of RNA polymerase B 4)
Gene: SRB4

Interactor 2: MED22 (P32570)
Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Suppressor of RNA polymerase B 6)
Gene: SRB6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.90 0.938

The method score is based on:

Property Details
Experiments 9660972, 20154708, 21725323, 11805826, 23123849, 11555651, 9671455, 8324825, 7479899, 8187178, 16429126, 16885025, 28575439, 31299084, 21498544, 23135281, 11383511, 15477388, 16554755, 37968396 and 1 others

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Identification Methods affinity chromatography technology, pull down, tandem affinity purification, biochemical, two hybrid
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Med17~Med22
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 3 others

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Homologous interactions 0

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Last updated: 15 Jul 2024