Interactor 1: MED17 (P32569)
Mediator of RNA polymerase II transcription subunit 17 (Mediator complex subunit 17) (Suppressor of RNA polymerase B 4)
Gene: SRB4

Interactor 2: MED18 (P32585)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (Suppressor of RNA polymerase B 5)
Gene: SRB5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.90 0.939

The method score is based on:

Property Details
Experiments 7877695, 21725323, 23123849, 20154708, 11555651, 9671455, 8324825, 7479899, 8187178, 16554755, 16429126, 16885025, 28575439, 18381891, 37968396, 23135281, 14759368, 14749386, 11383511, 19057509 and 3 others

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Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Med17~Med18
Common GO terms GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
and 5 others

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Homologous interactions 0

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Last updated: 15 Jul 2024