Interactor 1: MED17 (P32569)
Mediator of RNA polymerase II transcription subunit 17 (Mediator complex subunit 17) (Suppressor of RNA polymerase B 4)
Gene: SRB4

Interactor 2: MED31 (P38633)
Mediator of RNA polymerase II transcription subunit 31 (Hpr1 suppressor protein 1) (Mediator complex subunit 31)
Gene: SOH1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.90 0.889

The method score is based on:

Property Details
Experiments 11283351, 15477388, 16554755, 28575439, 37968396, 16429126
Identification Methods two hybrid pooling approach, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, molecular sieving
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med17~Med31
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024