Interactor 1: MED17 (P32569)
Mediator of RNA polymerase II transcription subunit 17 (Mediator complex subunit 17) (Suppressor of RNA polymerase B 4)
Gene: SRB4

Interactor 2: MED3 (P40356)
Mediator of RNA polymerase II transcription subunit 3 (Hyper-recombination suppressor protein 1) (Mediator complex subunit 3) (Poly-glutamine domain protein 1)
Gene: PGD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.55 0.712

The method score is based on:

Property Details
Experiments 9420330, 10949041, 16429126, 16554755, 28575439, 18381891, 37968396, 23135281
Identification Methods biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024