Interactor 1: MED17 (P32569)
Mediator of RNA polymerase II transcription subunit 17 (Mediator complex subunit 17) (Suppressor of RNA polymerase B 4)
Gene: SRB4

Interactor 2: MED11 (Q99278)
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)
Gene: MED11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.934

The method score is based on:

Property Details
Experiments 11283351, 20154708, 23123849, 21725323, 18691966, 33933450, 11555651, 16554755, 16429126, 16885025, 28575439, 37968396, 21498544, 23135281, 15477388
Identification Methods two hybrid pooling approach, pull down, two hybrid, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med11~Med17
Common GO terms GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024