Interactor 1: MED22 (P32570)
Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Suppressor of RNA polymerase B 6)
Gene: SRB6
Interactor 2: MED11 (Q99278)
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)
Gene: MED11
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.90 | 0.927 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10688190, 11805826, 15477388, 18691966, 21498544, 16429126, 33933450, 37968396, 24882805 |
| Identification Methods | two hybrid, tandem affinity purification, affinity chromatography technology, x-ray crystallography, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Med11~Med22 |
| Common GO terms | GO:0005634 - nucleus GO:0016592 - mediator complex GO:0032968 - positive regulation of transcription elongation by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly and 2 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
