HitPredict

Interactor 1: UBP4 (P32571)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Vacuole biogenesis protein SSV7)
Gene: DOA4

Interactor 2: SWD1 (P39706)
COMPASS component SWD1 (Complex proteins associated with SET1 protein SWD1) (Set1C component SWD1)
Gene: SWD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.80	0.717

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 926 Sc			1 426
+	Hs
		1070795 UBP36_HUMAN (563-925): 7.27e-97: 330: 25.14		RBBP5_HUMAN (1-397): 2.09e-78: 254: 28.15
+	Hs
		903231 UBP10_HUMAN (239-923): 1.01e-111: 363: 16.58		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Hs
		1058218 UBP10_HUMAN (239-923): 1.01e-111: 363: 16.58		SMU1_HUMAN (13-340): 3.07e-20: 94.9: 17.16
+	Hs
		1288358 UBP36_HUMAN (563-925): 7.27e-97: 330: 25.14		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		1288312 UBP42_HUMAN (455-926): 1.46e-90: 316: 19.20		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		1058268 UBP10_HUMAN (239-923): 1.01e-111: 363: 16.58		FBXW7_HUMAN (3-95): 3.57e-11: 67.2: 14.43
+	Hs
		1346960 UBP36_HUMAN (563-925): 7.27e-97: 330: 25.14		NLE1_HUMAN (243-415): 3.68e-22: 100: 10.92
+	Hs
		903571 UBP36_HUMAN (563-925): 7.27e-97: 330: 25.14		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Hs
		271161 UBP2_HUMAN (312-921): 2.26e-112: 360: 24.32		FBXW7_HUMAN (3-95): 3.57e-11: 67.2: 14.43
+	Sc
		630881 UBP10_YEAST (187-923): 7.53e-91: 307: 16.13		NLE1_YEAST (243-422): 2.36e-23: 104: 10.50
+	Hs
		197099 UBP36_HUMAN (563-925): 7.27e-97: 330: 25.14		PRP4_HUMAN (243-405): 2.82e-12: 70.3: 12.28
+	Hs
		1281441 UBP36_HUMAN (563-925): 7.27e-97: 330: 25.14		FBXW7_HUMAN (3-95): 3.57e-11: 67.2: 14.43
+	Hs
		259310 UBP12_HUMAN (556-921): 1.16e-92: 299: 23.50		WDR26_HUMAN (4-340): 4.17e-21: 98: 16.72
+	Hs
		905402 UBP46_HUMAN (556-921): 9.33e-92: 297: 21.93		WDR26_HUMAN (4-340): 4.17e-21: 98: 16.72
+	Mm
		1207984 UBP15_MOUSE (737-922): 9.4e-17: 87.4: 33.16		WDR26_MOUSE (4-340): 7.46e-21: 96.8: 16.72
+	Hs
		197012 UBP4_HUMAN (748-922): 8.57e-23: 107: 33.71		PRP4_HUMAN (243-405): 2.82e-12: 70.3: 12.28
+	Hs
		197111 UBP15_HUMAN (737-922): 1.28e-16: 87: 33.33		PRP4_HUMAN (243-405): 2.82e-12: 70.3: 12.28