HitPredict

Interactor 1: CSK (P32577)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase)
Gene: CSK

Interactor 2: PHAG1 (Q9JM80)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10801129
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	GO:0002250 - adaptive immune response GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 450 Rn			1 424
+	Mm
		782848 CSK_MOUSE (1-450): 0: 543: 99.33		PHAG1_MOUSE (1-424): 0: 771: 89.51
+	Mm
		763390 FYN_MOUSE (12-442): 5.95e-171: 492: 37.00		PHAG1_MOUSE (1-424): 0: 771: 89.51
+	Mm
		411925 LCK_MOUSE (2-445): 2.44e-169: 487: 38.21		PHAG1_MOUSE (1-424): 0: 771: 89.51
+	Hs
		782829 CSK_HUMAN (1-450): 0: 542: 98.44		PHAG1_HUMAN (1-424): 0: 695: 78.90
+	Mm
		639443 LYN_MOUSE (4-445): 1.57e-160: 464: 38.13		PHAG1_MOUSE (1-424): 0: 771: 89.51
+	Hs
		337571 ABL1_HUMAN (5-446): 6.56e-166: 498: 38.14		PHAG1_HUMAN (1-424): 0: 695: 78.90
+	Hs
		412375 FYN_HUMAN (12-442): 3.45e-171: 493: 37.00		PHAG1_HUMAN (1-424): 0: 695: 78.90
+	Hs
		523175 SRC_HUMAN (12-446): 2.96e-171: 493: 39.87		PHAG1_HUMAN (1-424): 0: 695: 78.90
+	Hs
		411873 LCK_HUMAN (2-445): 2.5e-170: 489: 38.65		PHAG1_HUMAN (1-424): 0: 695: 78.90
+	Hs
		789135 FRK_HUMAN (5-449): 6.71e-167: 480: 35.62		PHAG1_HUMAN (1-424): 0: 695: 78.90
+	Hs
		434038 LYN_HUMAN (4-445): 1.54e-160: 464: 37.77		PHAG1_HUMAN (1-424): 0: 695: 78.90