Interactor 1: MED18 (P32585)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (Suppressor of RNA polymerase B 5)
Gene: SRB5
Interactor 2: MED8 (P38304)
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)
Gene: MED8
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10688190, 16964259, 11555651, 16263706, 27688401, 18310102, 19934057, 37968396, 11383511, 15477388, 16554755, 16962561, 26138482, 17192271, 19057509, 33933450, 20123732, 21742760, 22693636, 15356001 |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, biochemical, x-ray crystallography, tandem affinity purification |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Med18~Med8 |
| Common GO terms | GO:0003712 - transcription coregulator activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0016592 - mediator complex GO:0032968 - positive regulation of transcription elongation by RNA polymerase II and 4 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
