HitPredict

Interactor 1: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Interactor 2: FES1 (P38260)
Hsp70 nucleotide exchange factor FES1 (Factor exchange for SSA1 protein 1)
Gene: FES1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	37968396, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000774 - adenyl-nucleotide exchange factor activity GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 693 Sc			1 290
+	Hs
		504872 HSP7C_HUMAN (2-645): 0: 851: 27.04		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		714085 HS71L_HUMAN (2-646): 0: 848: 26.69		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		483807 HS71B_HUMAN (2-643): 0: 843: 27.43		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Sp
		195082 HSP71_SCHPO (1-644): 0: 828: 26.88		FES1_SCHPO (1-237): 8.83e-52: 173: 29.63
+	Hs
		564199 HSP76_HUMAN (4-643): 0: 842: 26.28		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		871809 HSP72_HUMAN (2-644): 0: 840: 27.08		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		714444 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Sc
		493800 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Sc
		491027 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Dm
		365402 HSP71_DROME (6-631): 7.28e-74: 252: 29.23		Q95RI2_DROME (1-247): 8.95e-59: 191: 20.40
+	Dm
		947885 HSP70_DROME (6-631): 7.28e-74: 252: 29.23		Q95RI2_DROME (1-247): 8.95e-59: 191: 20.40