HitPredict

Interactor 1: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Interactor 2: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	18757749, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 693 Sc			1 268
+	Sc
		695965 HSP79_YEAST (1-677): 0: 992: 77.11		RPN10_YEAST (1-268): 3.42e-114: 330: 100.00
+	Zm
		43074 C4J410_MAIZE (2-684): 0: 852: 26.93		A0A1D6PF20_MAIZE (1-267): 4.17e-130: 377: 45.35
+	Hs
		503761 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Hs
		714157 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Dm
		874045 Q9VUC1_DROME (6-687): 1.49e-131: 409: 36.23		PSMD4_DROME (1-256): 5.75e-113: 332: 41.80
+	Sc
		493944 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		RPN10_YEAST (1-268): 3.42e-114: 330: 100.00
+	Sc
		491195 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		RPN10_YEAST (1-268): 3.42e-114: 330: 100.00