HitPredict

Interactor 1: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Interactor 2: HUL4 (P40985)
Probable E3 ubiquitin-protein ligase HUL4 (EC 2.3.2.26) (HECT ubiquitin ligase 4) (HECT-type E3 ubiquitin transferase HUL4)
Gene: HUL4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 693 Sc			1 892
+	Sc
		695991 HSP79_YEAST (1-677): 0: 992: 77.11		HUL4_YEAST (1-892): 0: 1353: 100.00
+	Sc
		491515 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		HUL4_YEAST (1-892): 0: 1353: 100.00
+	Hs
		125115 HSP7C_HUMAN (2-645): 0: 851: 27.04		WWP2_HUMAN (498-890): 3e-160: 492: 27.07
+	Hs
		504580 HSP7C_HUMAN (2-645): 0: 851: 27.04		ITCH_HUMAN (494-890): 1.13e-159: 492: 28.22
+	Hs
		503946 HSP7C_HUMAN (2-645): 0: 851: 27.04		UBE3A_HUMAN (410-891): 3.61e-155: 479: 32.03
+	Hs
		504792 HSP7C_HUMAN (2-645): 0: 851: 27.04		SMUF1_HUMAN (444-890): 4.95e-155: 475: 27.33
+	Sc
		695389 HSP7F_YEAST (1-693): 0: 829: 100.00		TOM1_YEAST (376-891): 5.59e-150: 492: 25.33
+	Hs
		504318 HSP7C_HUMAN (2-645): 0: 851: 27.04		HUWE1_HUMAN (449-891): 5.83e-142: 469: 26.61
+	Hs
		871538 HSP72_HUMAN (2-644): 0: 840: 27.08		UBE3A_HUMAN (410-891): 3.61e-155: 479: 32.03
+	Hs
		504222 HSP7C_HUMAN (2-645): 0: 851: 27.04		HECD2_HUMAN (400-891): 3.75e-146: 452: 33.60
+	Hs
		504920 HSP7C_HUMAN (2-645): 0: 851: 27.04		HERC5_HUMAN (472-890): 6.86e-53: 202: 30.28
+	Hs
		125610 HS105_HUMAN (6-687): 1.23e-133: 416: 36.05		WWP2_HUMAN (498-890): 3e-160: 492: 27.07
+	Hs
		714194 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		UBE3A_HUMAN (410-891): 3.61e-155: 479: 32.03
+	Hs
		714284 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		HUWE1_HUMAN (449-891): 5.83e-142: 469: 26.61
+	Hs
		1192142 HS105_HUMAN (6-687): 1.23e-133: 416: 36.05		HUWE1_HUMAN (449-891): 5.83e-142: 469: 26.61
+	Sc
		494807 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		TOM1_YEAST (376-891): 5.59e-150: 492: 25.33
+	Sc
		492242 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		TOM1_YEAST (376-891): 5.59e-150: 492: 25.33
+	Sc
		494037 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		RSP5_YEAST (498-890): 2.75e-152: 469: 29.32
+	Sc
		491309 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		RSP5_YEAST (498-890): 2.75e-152: 469: 29.32