HitPredict

Interactor 1: MYO1G (B0I1T2)
Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2 (mHag HA-2)]
Gene: MYO1G

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1018 Hs			1 1480
+	Hs
		297284 MYO1D_HUMAN (1-1016): 0: 1160: 60.04		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		117576 MYO1C_HUMAN (10-976): 0: 1044: 39.68		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529903 MYO5B_HUMAN (10-1013): 0: 1037: 28.23		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		64579 MYH7B_HUMAN (1-1018): 0: 1037: 27.05		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529959 MYO5A_HUMAN (10-1014): 0: 1036: 28.41		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529841 MYO1A_HUMAN (10-1018): 0: 1034: 38.19		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528682 MYH11_HUMAN (1-963): 0: 1030: 29.03		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528357 MYH6_HUMAN (1-1007): 0: 1025: 26.41		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		502902 MYH3_HUMAN (1-1006): 0: 1018: 25.82		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528675 MYH9_HUMAN (7-771): 0: 962: 33.50		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		214487 MYO1B_HUMAN (10-767): 0: 662: 46.50		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529052 MYO1E_HUMAN (10-734): 1.05e-175: 544: 41.77		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		522586 MYH7_HUMAN (692-1007): 7.07e-10: 65.7: 12.46		CFTR_HUMAN (1-1480): 0: 1031: 100.00