HitPredict

Interactor 1: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Interactor 2: SLT2 (Q00772)
Mitogen-activated protein kinase SLT2/MPK1 (MAP kinase MPK1) (EC 2.7.11.24)
Gene: SLT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	18478233, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 693 Sc			1 484
+	Sc
		695994 HSP79_YEAST (1-677): 0: 992: 77.11		SMK1_YEAST (15-359): 1.08e-106: 324: 43.30
+	Hs
		504011 HSP7C_HUMAN (2-645): 0: 851: 27.04		MK07_HUMAN (9-468): 1.21e-140: 425: 38.48
+	Hs
		504447 HSP7C_HUMAN (2-645): 0: 851: 27.04		MK15_HUMAN (16-461): 3.08e-136: 405: 31.78
+	Hs
		503480 HSP7C_HUMAN (2-645): 0: 851: 27.04		MK03_HUMAN (1-366): 4.38e-136: 398: 46.87
+	Rn
		600371 HSP7C_RAT (2-645): 0: 850: 27.04		MK03_RAT (14-366): 9.93e-136: 398: 48.02
+	Hs
		504142 HSP7C_HUMAN (2-645): 0: 851: 27.04		MK14_HUMAN (1-370): 3.04e-135: 396: 41.24
+	Hs
		503460 HSP7C_HUMAN (2-645): 0: 851: 27.04		CDK2_HUMAN (20-330): 3.15e-135: 393: 33.55
+	Rn
		600359 HS71L_RAT (2-646): 0: 846: 26.53		MK03_RAT (14-366): 9.93e-136: 398: 48.02
+	Rn
		483814 HS71B_RAT (3-666): 0: 845: 27.27		MK03_RAT (14-366): 9.93e-136: 398: 48.02
+	Hs
		564010 HSP76_HUMAN (4-643): 0: 842: 26.28		MK03_HUMAN (1-366): 4.38e-136: 398: 46.87
+	Rn
		538777 HSP72_RAT (2-644): 0: 837: 26.92		MK03_RAT (14-366): 9.93e-136: 398: 48.02
+	Sc
		691004 HSP7F_YEAST (1-693): 0: 829: 100.00		HOG1_YEAST (1-369): 2.36e-136: 402: 41.62
+	Sc
		694896 HSP7F_YEAST (1-693): 0: 829: 100.00		SMK1_YEAST (15-359): 1.08e-106: 324: 43.30
+	Hs
		714207 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		MK07_HUMAN (9-468): 1.21e-140: 425: 38.48
+	Rn
		291981 HSP74_RAT (6-650): 7.05e-137: 424: 38.47		MK03_RAT (14-366): 9.93e-136: 398: 48.02
+	Hs
		625169 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		CDK2_HUMAN (20-330): 3.15e-135: 393: 33.55
+	Sc
		493654 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		KDX1_YEAST (1-430): 2.82e-140: 411: 53.02
+	Sc
		493459 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		HOG1_YEAST (1-369): 2.36e-136: 402: 41.62
+	Sc
		494217 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		SMK1_YEAST (15-359): 1.08e-106: 324: 43.30
+	Sc
		493122 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		FUS3_YEAST (17-355): 2.81e-99: 304: 45.89