Interactor 1: TOR2 (P32600)
Serine/threonine-protein kinase TOR2 (EC 2.7.1.67) (EC 2.7.11.1) (Dominant rapamycin resistance protein 2) (Phosphatidylinositol 4-kinase TOR2) (PI4-kinase TOR2) (PI4K TOR2) (PtdIns-4-kinase TOR2) (Target of rapamycin kinase 2) (Temperature-sensitive CSG2 suppressor protein 14)
Gene: TOR2

Interactor 2: LST8 (P41318)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (Lethal with SEC13 protein 8)
Gene: LST8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 12719473, 14736892, 12631735, 12408816, 16002396, 27072897, 29170376, 18552287, 20489023
Identification Methods coimmunoprecipitation, affinity chromatography technology, biochemical, x-ray crystallography, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~WD40
Common GO terms GO:0001558 - regulation of cell growth
GO:0005886 - plasma membrane
GO:0007584 - response to nutrient
GO:0030950 - establishment or maintenance of actin cytoskeleton polarity
GO:0031929 - TOR signaling
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 2474
Sc

1 303
+ Sc
+ Sp
+ Sp
+ At
+ Hs
+ At
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs

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Last updated: 15 Jul 2024