HitPredict

Interactor 1: SEC17 (P32602)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) (Vesicular-fusion protein SEC17) (alpha-SNAP chaperone)
Gene: SEC17

Interactor 2: VPS45 (P38932)
Vacuolar protein sorting-associated protein 45
Gene: VPS45

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0031201 - SNARE complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 292 Sc			1 577
+	Hs
		873586 SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00		VPS45_HUMAN (1-576): 3.52e-174: 506: 36.27
+	Hs
		119619 SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00		STXB3_HUMAN (11-574): 2.9e-156: 461: 17.92
+	Hs
		873568 SNAA_HUMAN (12-291): 5.14e-101: 299: 35.00		SCFD1_HUMAN (21-576): 1.08e-146: 439: 18.46
+	Dm
		1095552 SNAP_DROME (3-289): 9.54e-100: 295: 32.40		SLY1_DROME (11-576): 4.75e-142: 427: 16.43
+	Hs
		1306207 SNAG_HUMAN (1-248): 1.09e-67: 214: 21.20		VPS45_HUMAN (1-576): 3.52e-174: 506: 36.27
+	Sc
		605788 SEC17_YEAST (1-292): 5.94e-97: 288: 100.00		SLY1_YEAST (32-576): 1.96e-125: 385: 20.23
+	Hs
		1261620 SNAG_HUMAN (1-248): 1.09e-67: 214: 21.20		SCFD1_HUMAN (21-576): 1.08e-146: 439: 18.46
+	Dm
		1096643 Q9U6R9_DROME (1-262): 1.1e-59: 194: 21.29		SLY1_DROME (11-576): 4.75e-142: 427: 16.43
+	Dm
		1096648 Q9VH25_DROME (23-262): 3.76e-56: 184: 21.49		SLY1_DROME (11-576): 4.75e-142: 427: 16.43