HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.980

Property	Details
Experiments	12200147, 9490418, 17082762, 25311859, 12589471, 16554755, 37968396, 20516210, 20061387, 21619884, 16712842
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, biochemical, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 398 Sc			1 467
+	Sc
		697104 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS10_YEAST (29-465): 2.46e-123: 367: 37.07
+	Rn
		1117330 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS7_RAT (12-467): 6.82e-131: 387: 70.18
+	Hs
		730225 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40
+	Hs
		730224 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40
+	Dm
		1359291 Q9V3W9_DROME (2-398): 1.44e-82: 260: 24.77		Q9V405_DROME (60-459): 2.26e-135: 397: 35.50
+	Rn
		1117333 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS6B_RAT (43-459): 4.73e-123: 366: 35.49
+	Hs
		798621 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Rn
		907221 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS8_RAT (81-464): 6.1e-121: 361: 44.53
+	Rn
		1104198 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		Q32PW9_RAT (85-463): 9.96e-120: 356: 42.48
+	Hs
		872249 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS8_HUMAN (81-464): 6.1e-121: 361: 44.53
+	Hs
		872250 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS10_HUMAN (81-463): 5.38e-120: 358: 42.04
+	Hs
		798620 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Hs
		872134 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS8_HUMAN (81-464): 6.1e-121: 361: 44.53
+	Sc
		697108 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Hs
		730383 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40
+	Hs
		798782 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Rn
		804049 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		TERA_RAT (33-442): 5.82e-80: 265: 28.13
+	Mm
		872327 RD23B_MOUSE (2-398): 4.71e-91: 282: 27.27		TERA_MOUSE (33-442): 6.46e-80: 265: 28.13
+	Hs
		872243 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		TERA_HUMAN (33-442): 6.46e-80: 265: 28.13
+	Hs
		872126 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		TERA_HUMAN (33-442): 6.46e-80: 265: 28.13