HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	11805826, 12198498, 37968396, 16429126
Identification Methods	tandem affinity purification, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 398 Sc			1 523
+	Rn
		61804 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		A6HIT6_RAT (4-513): 0: 545: 30.21
+	Hs
		198585 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		198584 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		198754 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		198746 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		198730 UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Mm
		539514 UBQL2_MOUSE (1-373): 3.8e-50: 180: 11.79		PSMD3_MOUSE (4-513): 0: 545: 30.21
+	Dm
		627146 Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38		PSMD3_DROME (1-513): 0: 521: 31.40
+	Hs
		198601 RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		1079635 NEDD8_HUMAN (2-62): 2.68e-15: 72.3: 24.59		CSN3_HUMAN (186-500): 7.68e-119: 358: 19.57