HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	11805826, 16554755, 37968396, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 398 Sc			1 437
+	Rn
		906973 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS4_RAT (1-437): 6.83e-132: 388: 70.68
+	Hs
		872248 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS4_HUMAN (1-437): 6.83e-132: 388: 70.68
+	Rn
		1117333 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS6B_RAT (47-431): 1.82e-129: 381: 49.09
+	Rn
		1104198 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		Q32PW9_RAT (61-435): 4.28e-129: 379: 40.80
+	Hs
		872133 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS4_HUMAN (1-437): 6.83e-132: 388: 70.68
+	Hs
		872250 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS10_HUMAN (52-435): 5.01e-129: 379: 40.37
+	Rn
		907221 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS8_RAT (38-432): 7.08e-126: 372: 42.42
+	Hs
		872249 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS8_HUMAN (38-432): 7.08e-126: 372: 42.42
+	Hs
		798621 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS6B_HUMAN (47-431): 1.61e-123: 366: 49.09
+	Sc
		697066 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS6B_YEAST (57-419): 9.33e-112: 337: 48.77
+	Hs
		872134 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS8_HUMAN (38-432): 7.08e-126: 372: 42.42
+	Hs
		798620 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS6B_HUMAN (47-431): 1.61e-123: 366: 49.09
+	Dm
		1359291 Q9V3W9_DROME (2-398): 1.44e-82: 260: 24.77		Q9V405_DROME (34-431): 9.95e-125: 369: 47.49
+	Sc
		697108 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS8_YEAST (106-429): 1.25e-104: 318: 49.38
+	Hs
		906946 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS4_HUMAN (1-437): 6.83e-132: 388: 70.68
+	Hs
		913367 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS10_HUMAN (52-435): 5.01e-129: 379: 40.37
+	Hs
		906941 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		PRS4_HUMAN (1-437): 6.83e-132: 388: 70.68
+	Hs
		907185 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS8_HUMAN (38-432): 7.08e-126: 372: 42.42
+	Hs
		798782 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS6B_HUMAN (47-431): 1.61e-123: 366: 49.09
+	Hs
		798776 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		PRS6B_HUMAN (47-431): 1.61e-123: 366: 49.09