HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.875

Property	Details
Experiments	10394357, 11389845, 16554755, 37968396
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0036503 - ERAD pathway GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 398 Sc			1 437
+	Rn
		907221 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS8_RAT (43-437): 1.18e-135: 397: 41.29
+	Hs
		872249 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS8_HUMAN (43-437): 1.18e-135: 397: 41.29
+	Hs
		872134 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS8_HUMAN (43-437): 1.18e-135: 397: 41.29
+	Rn
		1104198 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		Q32PW9_RAT (57-437): 2.88e-129: 379: 68.24
+	Hs
		872250 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS10_HUMAN (51-437): 1.51e-129: 381: 67.70
+	Rn
		906973 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS4_RAT (27-428): 6.56e-126: 373: 38.24
+	Hs
		872248 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS4_HUMAN (27-428): 6.56e-126: 373: 38.24
+	Hs
		872133 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS4_HUMAN (27-428): 6.56e-126: 373: 38.24
+	Sc
		697108 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS8_YEAST (73-437): 2.68e-99: 304: 44.89
+	Sc
		697067 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS7_YEAST (116-436): 9.22e-93: 289: 46.89
+	Sc
		636568 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		CDC48_YEAST (3-414): 2.64e-82: 271: 28.04
+	Rn
		804049 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		TERA_RAT (1-433): 3.26e-79: 263: 26.51
+	Mm
		872327 RD23B_MOUSE (2-398): 4.71e-91: 282: 27.27		TERA_MOUSE (23-433): 3.62e-79: 262: 26.83
+	Hs
		872243 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		TERA_HUMAN (23-433): 3.62e-79: 262: 26.83
+	Hs
		872126 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		TERA_HUMAN (23-433): 3.62e-79: 262: 26.83
+	Rn
		1117333 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS6B_RAT (1-123): 4.34e-09: 60.2: 8.03
+	Hs
		798621 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03
+	Hs
		798620 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03
+	Dm
		1359291 Q9V3W9_DROME (2-398): 1.44e-82: 260: 24.77		Q9V405_DROME (1-123): 2.61e-09: 60.9: 7.30
+	Hs
		798782 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03