HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	11805826, 37968396, 12198498, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 398 Sc			1 434
+	Rn
		78168 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		B5DEP6_RAT (1-433): 1.22e-98: 303: 41.01
+	Hs
		121715 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Hs
		121714 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Rn
		1117340 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		Q6PCT9_RAT (65-432): 1.08e-72: 235: 14.05
+	Hs
		872268 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PSMD6_HUMAN (65-432): 1.66e-73: 237: 13.78
+	Hs
		872158 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PSMD6_HUMAN (65-432): 1.66e-73: 237: 13.78
+	Hs
		121871 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Hs
		121867 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Hs
		121863 UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Dm
		1358524 Q9V3W9_DROME (2-398): 1.44e-82: 260: 24.77		PSMD6_DROME (53-432): 3.17e-69: 226: 13.35
+	Dm
		1180727 Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38		PSD11_DROME (3-433): 1.12e-99: 306: 44.44
+	Hs
		1062897 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PSMD6_HUMAN (65-432): 1.66e-73: 237: 13.78
+	Hs
		121730 RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Hs
		1062891 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		PSMD6_HUMAN (65-432): 1.66e-73: 237: 13.78
+	Hs
		1062884 UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76		PSMD6_HUMAN (65-432): 1.66e-73: 237: 13.78
+	Hs
		1311916 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		CSN4_HUMAN (58-430): 4.62e-65: 215: 15.25
+	Dm
		1358537 Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38		PSMD6_DROME (53-432): 3.17e-69: 226: 13.35
+	Hs
		121731 RL40_HUMAN (2-68): 1.02e-16: 77.7: 26.87		PSD11_HUMAN (1-433): 4.6e-98: 301: 41.01
+	Hs
		923997 RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73		PSMD6_HUMAN (65-432): 1.66e-73: 237: 13.78
+	Hs
		897254 NEDD8_HUMAN (2-62): 2.68e-15: 72.3: 24.59		CSN2_HUMAN (7-431): 4.9e-93: 289: 19.95