Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 25670679, 14759368, 19525970
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~Sec63, Helicase_C~Helicase_C, Helicase_C~Sec63, Helicase_PWI~Sec63, Sec63~Sec63
Common GO terms GO:0000388 - spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
GO:0000398 - mRNA splicing, via spliceosome
GO:0003676 - nucleic acid binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
and 5 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2163
Sc

1 2163
+ Hs
+ Hs
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+ Hs
+ At
+ Sc
+ Sp
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Sp
+ Hs
+ Sp
+ Hs

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Last updated: 15 Jul 2024