Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: PRP8 (P33334)
Pre-mRNA-splicing factor 8
Gene: PRP8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 19098916, 19525970, 11290703, 23704370, 23727230, 17934474, 18953335, 16429126, 16373487, 21764848, 23442228, 25670679, 11720284, 26637280, 10449419, 16554755, 16540695, 27072132, 27880071, 37968396 and 1 others

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Identification Methods pull down, anti bait coimmunoprecipitation, coimmunoprecipitation, two hybrid, molecular sieving, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, biochemical and 1 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~PROCT, Helicase_C~PROCT, PROCT~Sec63
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005682 - U5 snRNP
GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 2163
Sc

1 2413
+ Hs
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Sp
+ Sc

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Last updated: 15 Jul 2024