HitPredict

Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: NCBP2 (Q08920)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: CBC2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	37968396, 24500206, 21558325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2163 Sc			1 208
+	Hs
		272072 U520_HUMAN (16-2163): 0: 1597: 38.84		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	Sc
		697283 BRR2_YEAST (1-2163): 0: 1534: 100.00		HSH49_YEAST (41-119): 2.34e-25: 99.7: 28.75
+	Sp
		678721 BRR2_SCHPO (5-2162): 0: 1396: 41.00		PABP_SCHPO (3-179): 2.44e-20: 90.1: 10.27
+	Hs
		516589 ASCC3_HUMAN (65-2162): 0: 1382: 31.01		PABP1_HUMAN (47-175): 1.75e-20: 90.5: 14.60
+	Sc
		810941 MTR4_YEAST (364-927): 1.48e-92: 329: 20.07		NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00
+	Sp
		143177 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		NCBP2_SCHPO (14-183): 2.71e-44: 147: 50.00
+	Hs
		571369 DDX5_HUMAN (1344-1752): 6.23e-93: 317: 11.35		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	Sp
		143184 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		YKCG_SCHPO (43-205): 1.2e-33: 125: 19.63
+	Mm
		857323 DDX17_MOUSE (1345-1753): 1.48e-97: 332: 11.35		TIA1_MOUSE (41-180): 1.95e-20: 89.7: 20.00
+	Sp
		145110 MTR4_SCHPO (315-927): 2.8e-88: 316: 19.28		PAB2_SCHPO (35-119): 7.62e-28: 104: 30.59
+	Sp
		143003 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		PAB2_SCHPO (35-119): 7.62e-28: 104: 30.59
+	Hs
		786913 MTREX_HUMAN (355-1000): 4.3e-76: 278: 18.12		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	Mm
		857351 Q8BTS0_MOUSE (1344-1752): 8.2e-93: 317: 11.35		TIA1_MOUSE (41-180): 1.95e-20: 89.7: 20.00
+	Sp
		143097 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		PABP_SCHPO (3-179): 2.44e-20: 90.1: 10.27
+	Hs
		1313230 DDX23_HUMAN (1275-1768): 3.27e-82: 292: 13.30		RBM19_HUMAN (42-113): 4.9e-09: 57.4: 36.00
+	Sc
		622345 PRP22_YEAST (1343-1825): 7.15e-45: 180: 10.74		NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00