HitPredict

Interactor 1: GLRX4 (P32642)
Monothiol glutaredoxin-4
Gene: GRX4

Interactor 2: GLRX3 (Q03835)
Monothiol glutaredoxin-3
Gene: GRX3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 37968396, 17074835, 23045394
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Glutaredoxin~Glutaredoxin, Thioredoxin~Thioredoxin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006879 - intracellular iron ion homeostasis
GO:0015036 - disulfide oxidoreductase activity
and 7 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 244
Sc

1 250
+ Sc
+ Sc
+ Sp
+ Hs
+ At
+ Zm
+ At
+ Cr
+ Hs
+ Ec
+ Sc
+ Sc
+ Hs
+ At
+ Hs
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024