HitPredict

Interactor 1: CHD1 (P32657)
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)
Gene: CHD1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.933

Property	Details
Experiments	29019976, 30005873, 37968396, 22199229, 22922743, 21179020
Identification Methods	pull down, unspecified method, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1468 Sc			1 136
+	Sc
		697376 CHD1_YEAST (1-1468): 0: 1114: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		935262 CHD8_HUMAN (2-1377): 0: 934: 26.15		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952639 CHD8_HUMAN (2-1377): 0: 934: 26.15		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		952373 CHD9_HUMAN (20-1378): 0: 921: 26.06		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Sp
		144536 HRP3_SCHPO (7-1463): 0: 914: 46.24		H31_SCHPO (1-136): 1.17e-59: 182: 92.65
+	Dm
		356088 CHD1_DROME (47-1466): 0: 900: 30.86		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Hs
		151487 CHD2_HUMAN (5-1468): 0: 876: 31.11		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		151396 CHD1_HUMAN (45-1468): 0: 837: 32.83		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		151399 CHD1_HUMAN (45-1468): 0: 837: 32.83		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		151419 CHD1_HUMAN (45-1468): 0: 837: 32.83		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Mm
		770296 CHD1_MOUSE (44-1468): 0: 834: 32.36		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Hs
		151392 CHD1_HUMAN (45-1468): 0: 837: 32.83		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		658647 SMCA1_HUMAN (253-1259): 0: 778: 27.19		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Mm
		935460 SMCA5_MOUSE (243-1274): 0: 778: 26.57		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Hs
		229359 SMCA5_HUMAN (245-1274): 0: 777: 26.33		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		658651 SMCA1_HUMAN (253-1259): 0: 778: 27.19		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Mm
		952763 SMCA5_MOUSE (243-1274): 0: 778: 26.57		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Mm
		952266 SMCA5_MOUSE (243-1274): 0: 778: 26.57		H32_MOUSE (1-136): 6.6e-61: 185: 88.97
+	Hs
		658641 SMCA1_HUMAN (253-1259): 0: 778: 27.19		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		229341 SMCA5_HUMAN (245-1274): 0: 777: 26.33		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73