HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: LSB3 (P43603)
LAS seventeen-binding protein 3 (LAS17-binding protein 3)
Gene: LSB3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.972

Property	Details
Experiments	11743162, 12388763, 11805826, 16429126, 19841731, 18467557, 34887356, 14737190
Identification Methods	two hybrid, tandem affinity purification, affinity chromatography technology, protein complementation assay, peptide array, two hybrid array, two hybrid pooling approach, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005935 - cellular bud neck GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1244 Sc			1 459
+	Sc
		697889 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		YSC84_YEAST (1-458): 1.59e-124: 372: 62.24
+	Sc
		697931 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		RV167_YEAST (403-458): 5.35e-19: 91.4: 46.43
+	Mm
		88459 D3Z656_MOUSE (467-973): 5.94e-11: 69.5: 6.43		SH3G2_MOUSE (93-459): 7.42e-38: 143: 14.79
+	Mm
		250689 ATX2_MOUSE (155-1241): 1.33e-10: 68.4: 8.76		SH3G2_MOUSE (93-459): 7.42e-38: 143: 14.79
+	Hs
		203248 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		SH3G1_HUMAN (93-459): 5.76e-39: 146: 17.03
+	Hs
		1052269 ATX2L_HUMAN (545-1243): 2.66e-14: 80.3: 9.59		SRC8_HUMAN (208-458): 1.05e-31: 129: 15.95
+	Hs
		1305672 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		SH3G2_HUMAN (93-459): 1.18e-37: 142: 15.14
+	Hs
		203249 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		SH3G2_HUMAN (93-459): 1.18e-37: 142: 15.14
+	Rn
		192354 SYNJ1_RAT (481-973): 4.59e-09: 63.4: 8.93		SH3G2_RAT (93-459): 1.73e-37: 142: 14.52
+	Hs
		1305673 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		SH3G3_HUMAN (94-459): 7.9e-37: 140: 14.09
+	Ce
		70017 G5EBN5_CAEEL (879-1243): 1.28e-11: 71.7: 12.60		SH3GH_CAEEL (93-459): 2.8e-34: 133: 13.60
+	Mm
		88460 D3Z656_MOUSE (467-973): 5.94e-11: 69.5: 6.43		SH3G3_MOUSE (94-459): 9.01e-35: 134: 13.01
+	Rn
		192356 SYNJ1_RAT (481-973): 4.59e-09: 63.4: 8.93		SH3G3_RAT (94-459): 3.4e-35: 135: 13.82
+	Hs
		203262 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		PACN2_HUMAN (157-459): 1.05e-33: 134: 17.08
+	Hs
		203246 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		SH3Y1_HUMAN (309-458): 2.03e-23: 102: 20.67
+	Hs
		203192 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		SRBS2_HUMAN (201-459): 9e-21: 97.6: 17.60
+	Hs
		203224 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		MYO1E_HUMAN (260-459): 1.46e-18: 91: 23.15
+	Hs
		203228 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		ITSN1_HUMAN (282-459): 6.18e-12: 70.4: 18.03
+	Dm
		993211 Q9VUH6_DROME (866-1244): 2.09e-10: 67.5: 11.69		GRAP_DROME (407-456): 7.37e-11: 63.5: 56.00
+	Hs
		1200907 Q86V38_HUMAN (649-1244): 2.59e-09: 64.1: 7.89		STAC_HUMAN (406-457): 2.14e-09: 61.2: 51.92