HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: ARK1 (P53974)
Actin-regulating kinase 1 (EC 2.7.11.1)
Gene: ARK1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	16319894, 17978096, 20489023
Identification Methods	enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000147 - actin cortical patch assembly GO:0005737 - cytoplasm GO:0030479 - actin cortical patch GO:0043332 - mating projection tip
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 638
+	Sc
		697945 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		PRK1_YEAST (1-518): 1.09e-159: 480: 48.06
+	Sc
		697910 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		AKL1_YEAST (1-529): 2.84e-103: 340: 32.23
+	Sc
		692229 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		PRK1_YEAST (1-518): 1.09e-159: 480: 48.06
+	Sc
		692241 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		ARK1_YEAST (1-638): 2.28e-140: 424: 100.00
+	Hs
		1101676 WNK1_HUMAN (715-1108): 1.54e-33: 143: 13.73		AAK1_HUMAN (11-412): 1.3e-103: 338: 30.45
+	Sc
		692220 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		AKL1_YEAST (1-529): 2.84e-103: 340: 32.23
+	Ce
		105413 Q95PW9_CAEEL (8-155): 1.65e-46: 174: 21.88		SEL5_CAEEL (12-291): 5.08e-37: 150: 37.32
+	Hs
		161716 WNK1_HUMAN (715-1108): 1.54e-33: 143: 13.73		GAK_HUMAN (11-302): 4.37e-39: 156: 34.88
+	Hs
		161640 SC24C_HUMAN (619-982): 3.04e-09: 63.6: 11.41		GAK_HUMAN (11-302): 4.37e-39: 156: 34.88