HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	19841731, 37968396
Identification Methods	two hybrid, affinity chromatography technology, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0043332 - mating projection tip
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 1219
+	Sc
		697903 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		MYO3_YEAST (1-1205): 0: 1087: 72.08
+	Sc
		692248 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		MYO5_YEAST (1-1219): 0: 1126: 100.00
+	Hs
		725018 WNK1_HUMAN (715-1108): 1.54e-33: 143: 13.73		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Sc
		692216 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		MYO3_YEAST (1-1205): 0: 1087: 72.08
+	Sp
		194039 YFHH_SCHPO (203-1209): 2.96e-21: 103: 7.48		MYO1_SCHPO (1-1219): 0: 1043: 51.57
+	Hs
		203224 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		MYO1E_HUMAN (24-1145): 0: 1052: 36.98