HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: ENT2 (Q05785)
Epsin-2
Gene: ENT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	19841731, 32400111, 37968396
Identification Methods	two hybrid, fluorescent resonance energy transfer, affinity chromatography technology, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000147 - actin cortical patch assembly GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0043332 - mating projection tip
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 613
+	Sc
		698031 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		ENT1_YEAST (1-514): 2.63e-90: 288: 50.97
+	Sc
		692249 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		ENT2_YEAST (1-613): 2.84e-94: 303: 100.00
+	Sc
		692257 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		ENT1_YEAST (1-514): 2.63e-90: 288: 50.97
+	Hs
		203228 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		ITSN1_HUMAN (123-593): 6.84e-49: 186: 15.39
+	Mm
		1351630 PCLO_MOUSE (151-1049): 1.74e-16: 88: 8.79		PCLO_MOUSE (131-612): 2.49e-13: 75.8: 9.91
+	Dm
		113976 M9PB30_DROME (125-851): 1.04e-16: 88.8: 7.50		M9PB30_DROME (157-613): 2.69e-09: 62.7: 7.50
+	Sp
		1013617 PAN1_SCHPO (402-980): 3.44e-09: 63.8: 7.08		PAN1_SCHPO (216-573): 2.21e-13: 75.9: 13.09
+	Hs
		1057773 NCOA6_HUMAN (128-1210): 2.42e-11: 70.7: 7.02		KMT2C_HUMAN (155-605): 1.1e-09: 63.9: 9.49