HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: INP53 (Q12271)
Polyphosphatidylinositol phosphatase INP53 (Suppressor of PMA1 protein 2) (Synaptojanin-like protein 3) [Includes: SAC1-like phosphoinositide phosphatase (EC 3.1.3.-); Phosphatidylinositol 4,5-bisphosphate 5-phosphatase (EC 3.1.3.36)]
Gene: INP53

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	25518934, 19841731
Identification Methods	affinity chromatography technology, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006897 - endocytosis GO:0030479 - actin cortical patch
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 1107
+	Sc
		697967 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		INP52_YEAST (1-1098): 0: 1119: 57.27
+	Sc
		697948 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		INP51_YEAST (1-987): 0: 843: 29.27
+	Ce
		105280 Q95PW9_CAEEL (8-155): 1.65e-46: 174: 21.88		SYNJ_CAEEL (35-1079): 0: 896: 25.54
+	Hs
		968220 WNK1_HUMAN (715-1108): 1.54e-33: 143: 13.73		OCRL_HUMAN (542-1055): 1.38e-152: 480: 24.53