HitPredict

Interactor 1: B1AT92 (B1AT92)
Growth factor receptor bound protein 2
Gene: Grb2

Interactor 2: GAB2 (Q9Z1S8)
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (PH domain-containing adaptor molecule p97)
Gene: GAB2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20697350
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~SH3_1, PH~SH3_9
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 203 Mm			1 665
+	Mm
		1141175 GRB2_MOUSE (1-203): 2.3e-68: 210: 86.64		GAB2_MOUSE (1-665): 2.53e-180: 529: 100.00
+	Mm
		1114082 GRB2_MOUSE (1-203): 2.3e-68: 210: 86.64		Q3ZB59_MOUSE (1-665): 6.22e-180: 528: 99.85
+	Hs
		924959 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		GAB2_HUMAN (4-665): 1.34e-176: 520: 90.67
+	Mm
		639464 LYN_MOUSE (3-188): 9.3e-41: 146: 28.08		GAB2_MOUSE (1-665): 2.53e-180: 529: 100.00
+	Mm
		1141170 GRB2_MOUSE (1-203): 2.3e-68: 210: 86.64		GAB1_MOUSE (5-664): 7.18e-125: 387: 36.23
+	Hs
		924547 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		433750 LYN_HUMAN (3-188): 3.59e-40: 144: 28.57		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		924730 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		GAB3_HUMAN (1-656): 5.85e-93: 301: 31.55
+	Hs
		337512 ABL1_HUMAN (4-151): 1.4e-50: 177: 32.68		GAB3_HUMAN (1-656): 5.85e-93: 301: 31.55
+	Hs
		433922 LYN_HUMAN (3-188): 3.59e-40: 144: 28.57		GAB3_HUMAN (1-656): 5.85e-93: 301: 31.55
+	Hs
		203218 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		SYNJ1_HUMAN (123-640): 1.41e-53: 201: 14.86
+	Hs
		924876 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		PKHA2_HUMAN (3-227): 2.69e-44: 166: 21.83
+	Hs
		924640 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		PKHA7_HUMAN (1-549): 2.93e-39: 157: 13.53
+	Hs
		924627 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		PKHS1_HUMAN (8-314): 1.04e-38: 151: 19.02
+	Dm
		993221 GRAP_DROME (1-201): 2.84e-58: 184: 58.49		DOS_DROME (7-620): 1.69e-43: 169: 17.92
+	Hs
		434015 LYN_HUMAN (3-188): 3.59e-40: 144: 28.57		PKHA5_HUMAN (1-402): 1.93e-49: 188: 16.26
+	Hs
		433831 LYN_HUMAN (3-188): 3.59e-40: 144: 28.57		PKHA7_HUMAN (1-549): 2.93e-39: 157: 13.53
+	Hs
		434016 LYN_HUMAN (3-188): 3.59e-40: 144: 28.57		PKHA1_HUMAN (9-164): 6.12e-35: 139: 24.05
+	Hs
		924702 GRB2_HUMAN (1-203): 3.26e-68: 209: 90.78		SESQ1_HUMAN (8-117): 3.45e-13: 72: 27.43
+	Hs
		297808 LYN_HUMAN (3-188): 3.59e-40: 144: 28.57		K0754_HUMAN (99-564): 2.73e-26: 117: 11.89